Downregulation of NSD3 (WHSC1L1) inhibits cell proliferation and migration via ERK1/2 deactivation and decreasing CAPG expression in colorectal cancer cells

Purpose: NSD3 (WHSC1L1) is a protein lysine methyltransferase that is recurrently amplified (8p11.23) in several cancer types, and its upregulation is involved in tumor cell proliferation, metastasis, and epithelial-mesenchymal transition (EMT). We aimed to evaluate its potential function as an onco...

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Detalles Bibliográficos
Autores principales: Yi, Lanjuan, Yi, Lanjie, Liu, Qing, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535100/
https://www.ncbi.nlm.nih.gov/pubmed/31190890
http://dx.doi.org/10.2147/OTT.S191732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535100/
https://www.ncbi.nlm.nih.gov/pubmed/31190890
http://dx.doi.org/10.2147/OTT.S191732

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