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An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy
An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice.
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535376/ https://www.ncbi.nlm.nih.gov/pubmed/30475349 http://dx.doi.org/10.1038/nbt.4302 |