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An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy
An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice.
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535376/ https://www.ncbi.nlm.nih.gov/pubmed/30475349 http://dx.doi.org/10.1038/nbt.4302 |
| _version_ | 1783421562101170176 |
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| author | Xu, Bo Ma, Rui Russell, Luke Yoo, Ji Young Han, Jianfeng Cui, Hanwei Yi, Ping Zhang, Jianying Nakashima, Hiroshi Dai, Hongsheng Chiocca, E. Antonio Kaur, Balveen Caligiuri, Michael A Yu, Jianhua |
| author_facet | Xu, Bo Ma, Rui Russell, Luke Yoo, Ji Young Han, Jianfeng Cui, Hanwei Yi, Ping Zhang, Jianying Nakashima, Hiroshi Dai, Hongsheng Chiocca, E. Antonio Kaur, Balveen Caligiuri, Michael A Yu, Jianhua |
| author_sort | Xu, Bo |
| collection | PubMed |
| description | An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice. |
| format | Online Article Text |
| id | pubmed-6535376 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-65353762019-05-26 An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy Xu, Bo Ma, Rui Russell, Luke Yoo, Ji Young Han, Jianfeng Cui, Hanwei Yi, Ping Zhang, Jianying Nakashima, Hiroshi Dai, Hongsheng Chiocca, E. Antonio Kaur, Balveen Caligiuri, Michael A Yu, Jianhua Nat Biotechnol Article An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice. 2018-11-26 /pmc/articles/PMC6535376/ /pubmed/30475349 http://dx.doi.org/10.1038/nbt.4302 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
| spellingShingle | Article Xu, Bo Ma, Rui Russell, Luke Yoo, Ji Young Han, Jianfeng Cui, Hanwei Yi, Ping Zhang, Jianying Nakashima, Hiroshi Dai, Hongsheng Chiocca, E. Antonio Kaur, Balveen Caligiuri, Michael A Yu, Jianhua An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title | An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title_full | An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title_fullStr | An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title_full_unstemmed | An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title_short | An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy |
| title_sort | oncolytic herpes virus expressing e-cadherin resists nk cell clearance and improves viral spread and glioblastoma virotherapy |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535376/ https://www.ncbi.nlm.nih.gov/pubmed/30475349 http://dx.doi.org/10.1038/nbt.4302 |
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