An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy

An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice.

Detalles Bibliográficos
Autores principales: Xu, Bo, Ma, Rui, Russell, Luke, Yoo, Ji Young, Han, Jianfeng, Cui, Hanwei, Yi, Ping, Zhang, Jianying, Nakashima, Hiroshi, Dai, Hongsheng, Chiocca, E. Antonio, Kaur, Balveen, Caligiuri, Michael A, Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535376/
https://www.ncbi.nlm.nih.gov/pubmed/30475349
http://dx.doi.org/10.1038/nbt.4302

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