Tissue Distribution and Penetration of Isavuconazole at the Site of Infection in Experimental Invasive Aspergillosis in Mice with Underlying Chronic Granulomatous Disease

Isavuconazole, the active moiety of the prodrug isavuconazonium sulfate, has potent activity against a wide spectrum of fungal pathogens and is approved for the treatment of invasive aspergillosis, yet little is known about the tissue penetration of isavuconazole at the target sites of infection. He...

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Detalles Bibliográficos
Autores principales: Lee, Annie, Prideaux, Brendan, Lee, Min Hee, Zimmerman, Matthew, Dolgov, Enriko, Perlin, David S., Zhao, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535567/
https://www.ncbi.nlm.nih.gov/pubmed/30988140
http://dx.doi.org/10.1128/AAC.00524-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535567/
https://www.ncbi.nlm.nih.gov/pubmed/30988140
http://dx.doi.org/10.1128/AAC.00524-19

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