Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma

Telomeres play important roles in genome stability and cell proliferation. High risk neuroblastoma (HRNB), an aggressive childhood cancer, is especially reliant on telomere maintenance. Three recurrent genetic aberrations in HRNB (MYCN amplification, TERT re-arrangements, and ATRX mutations) are mut...

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Detalles Bibliográficos
Autores principales: Yu, Eun Young, Cheung, Irene Y., Feng, Yi, Rabie, Mohamed O., Roboz, Gail J., Guzman, Monica L., Cheung, Nai-Kong V., Lue, Neal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535646/
https://www.ncbi.nlm.nih.gov/pubmed/31128432
http://dx.doi.org/10.1016/j.neo.2019.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535646/
https://www.ncbi.nlm.nih.gov/pubmed/31128432
http://dx.doi.org/10.1016/j.neo.2019.04.002

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