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HEATR1 modulates cell survival in non-small cell lung cancer via activation of the p53/PUMA signaling pathway

Aim: To determine the mechanisms of HEATR1 on cell survival in non-small cell lung cancer (NSCLC). Methods: HEATR1 mRNA expression levels in 57 pairs of NSCLC tumor and adjacent normal lung tissues were analyzed using the TCGA database. The effect of HEATR1 inhibition on cell proliferation, apoptosi...

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Detalles Bibliográficos
Autores principales: He, Saifei, Ma, Xing, Ye, Ying, Zhang, Miao, Zhuang, Juhua, Song, Yanan, Xia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535672/
https://www.ncbi.nlm.nih.gov/pubmed/31190896
http://dx.doi.org/10.2147/OTT.S195826