Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer

OBJECTIVE: Leucyl-tRNA synthetase (LRS) is an aminoacyl-tRNA synthetase catalyzing ligation of leucine to its cognate tRNA and is involved in the activation of mTORC1 by sensing cytoplasmic leucine. In this study, the usefulness of LRS as a therapeutic target of non-small cell lung cancer (NSCLC) an...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Lee, Jin Gu, Lee, Jung Mo, Kim, Arum, Yoo, Hee Chan, Kim, Kibum, Lee, Minji, Lee, Chulho, Han, Gyoonhee, Han, Jung Min, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535710/
https://www.ncbi.nlm.nih.gov/pubmed/31205503
http://dx.doi.org/10.1177/1758835919846798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535710/
https://www.ncbi.nlm.nih.gov/pubmed/31205503
http://dx.doi.org/10.1177/1758835919846798

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