Tofacitinib in the treatment of ulcerative colitis: efficacy and safety from clinical trials to real-world experience

Tofacitinib is an oral small molecule directed against the JAK/STAT pathway, blocking the inflammatory cascade. Oral formulation of tofacitinib has recently been approved for the treatment of patients with moderate–severe ulcerative colitis. Its efficacy and safety have been demonstrated in three ph...

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Detalles Bibliográficos
Autores principales: D’Amico, Ferdinando, Parigi, Tommaso Lorenzo, Fiorino, Gionata, Peyrin-Biroulet, Laurent, Danese, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535722/
https://www.ncbi.nlm.nih.gov/pubmed/31205486
http://dx.doi.org/10.1177/1756284819848631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535722/
https://www.ncbi.nlm.nih.gov/pubmed/31205486
http://dx.doi.org/10.1177/1756284819848631

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