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Tofacitinib in the treatment of ulcerative colitis: efficacy and safety from clinical trials to real-world experience
Tofacitinib is an oral small molecule directed against the JAK/STAT pathway, blocking the inflammatory cascade. Oral formulation of tofacitinib has recently been approved for the treatment of patients with moderate–severe ulcerative colitis. Its efficacy and safety have been demonstrated in three ph...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535722/ https://www.ncbi.nlm.nih.gov/pubmed/31205486 http://dx.doi.org/10.1177/1756284819848631 |