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Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling

Acetaminophen (APAP) overdose is one of the most common causes of drug-induced acute liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) on APAP-induced hepatic damage, SAC was administered by daily intraperitoneal (i.p.) injection for 6 days before the AP...

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Detalles Bibliográficos
Autores principales: Wu, Chien-Ta, Deng, Jeng-Shyan, Huang, Wen-Chin, Shieh, Po-Chou, Chung, Mei-Ing, Huang, Guan-Jhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535820/
https://www.ncbi.nlm.nih.gov/pubmed/31214283
http://dx.doi.org/10.1155/2019/9056845