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Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines

BACKGROUND: Endoplasmic reticulum stress has a profound effect on cancer cell proliferation and survival, and also has the capacity to activate cells of the adaptive immune system. Multimodal treatment methods that utilize and combine conventional cancer therapies with antigen-specific immunotherapi...

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Detalles Bibliográficos
Autores principales: Lee, Sung Yong, Oh, Jee Youn, Kang, Tae Heung, Shin, Hyun Seock, Cheng, Max A., Farmer, Emily, Wu, T.-C., Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535840/
https://www.ncbi.nlm.nih.gov/pubmed/31133013
http://dx.doi.org/10.1186/s12929-019-0536-7