Machine Learning-Enhanced T Cell Neoepitope Discovery for Immunotherapy Design

Immune responses mediated by T cells are aimed at specific peptides, designated T cell epitopes, that are recognized when bound to human leukocyte antigen (HLA) molecules. The HLA genes are remarkably polymorphic in the human population allowing a broad and fine-tuned capacity to bind a wide array o...

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Detalles Bibliográficos
Autores principales: Martins, Joana, Magalhães, Carlos, Rocha, Miguel, Osório, Nuno S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Short Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535895/
https://www.ncbi.nlm.nih.gov/pubmed/31205413
http://dx.doi.org/10.1177/1176935119852081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535895/
https://www.ncbi.nlm.nih.gov/pubmed/31205413
http://dx.doi.org/10.1177/1176935119852081

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