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Machine Learning-Enhanced T Cell Neoepitope Discovery for Immunotherapy Design
Immune responses mediated by T cells are aimed at specific peptides, designated T cell epitopes, that are recognized when bound to human leukocyte antigen (HLA) molecules. The HLA genes are remarkably polymorphic in the human population allowing a broad and fine-tuned capacity to bind a wide array o...
Autores principales: | Martins, Joana, Magalhães, Carlos, Rocha, Miguel, Osório, Nuno S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535895/ https://www.ncbi.nlm.nih.gov/pubmed/31205413 http://dx.doi.org/10.1177/1176935119852081 |
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