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Doxorubicin-Induced Cancer Cell Senescence Shows a Time Delay Effect and Is Inhibited by Epithelial-Mesenchymal Transition (EMT)

BACKGROUND: Senescence is a natural barrier for the body to resist the malignant transformation of its own cells. This work investigated the senescence characteristics of cancer cells in vitro. MATERIAL/METHODS: Human cervical cancer HeLa cells were treated with different concentrations of doxorubic...

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Detalles Bibliográficos
Autores principales: Hu, Xuerui, Zhang, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536035/
https://www.ncbi.nlm.nih.gov/pubmed/31092810
http://dx.doi.org/10.12659/MSM.914295