Calotropin activates YAP through downregulation of LATS1 in colorectal cancer cells

Objectives: Calotropin (CTP), a natural product isolated from Calotropis gigantea, has been identified as a potential anticancer agent. In this study, we aimed to investigate the effect CTP on colorectal cancer and the role of Yes-associated protein (YAP) in CTP-inhibited cell proliferation. Methods...

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Detalles Bibliográficos
Autores principales: Zhou, Limin, Cai, Luliang, Guo, Yanzi, Zhang, Huanyu, Wang, Peng, Yi, Guohui, Huang, Yonghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536122/
https://www.ncbi.nlm.nih.gov/pubmed/31190898
http://dx.doi.org/10.2147/OTT.S200873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536122/
https://www.ncbi.nlm.nih.gov/pubmed/31190898
http://dx.doi.org/10.2147/OTT.S200873

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