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miR-140-3p Knockdown Suppresses Cell Proliferation and Fibrogenesis in Hepatic Stellate Cells via PTEN-Mediated AKT/mTOR Signaling

PURPOSE: Liver fibrosis is a major cause of morbidity and mortality and the outcome of various chronic liver diseases. Activation of hepatic stellate cells (HSCs) is the key event in liver fibrosis. Studies have confirmed that miR-140-3p plays a potential regulatory effect on HSC activation. However...

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Detalles Bibliográficos
Autores principales: Wu, Shi-Min, Li, Tian-Hong, Yun, Hao, Ai, Hong-Wu, Zhang, Ke-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536388/
https://www.ncbi.nlm.nih.gov/pubmed/31124340
http://dx.doi.org/10.3349/ymj.2019.60.6.561