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miR-140-3p Knockdown Suppresses Cell Proliferation and Fibrogenesis in Hepatic Stellate Cells via PTEN-Mediated AKT/mTOR Signaling
PURPOSE: Liver fibrosis is a major cause of morbidity and mortality and the outcome of various chronic liver diseases. Activation of hepatic stellate cells (HSCs) is the key event in liver fibrosis. Studies have confirmed that miR-140-3p plays a potential regulatory effect on HSC activation. However...
Autores principales: | Wu, Shi-Min, Li, Tian-Hong, Yun, Hao, Ai, Hong-Wu, Zhang, Ke-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536388/ https://www.ncbi.nlm.nih.gov/pubmed/31124340 http://dx.doi.org/10.3349/ymj.2019.60.6.561 |
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