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5‐ARI induces autophagy of prostate epithelial cells through suppressing IGF‐1 expression in prostate fibroblasts

OBJECTIVES: 5α‐reductase inhibitor (5‐ARI) is a commonly used medicine in the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Our study mainly focuses on the mechanism of BPH development after 5ARI treatment. MATERIALS AND METHODS: Prostate specim...

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Detalles Bibliográficos
Autores principales: Yang, Bo‐Yu, Jiang, Chen‐Yi, Dai, Chen‐Yun, Zhao, Rui‐Zhe, Wang, Xing‐Jie, Zhu, Yi‐Ping, Qian, Yu‐Xin, Yin, Fu‐Li, Fu, Xiang‐Yu, Jing, Yi‐Feng, Han, Bang‐Min, Xia, Shu‐Jie, Ruan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536403/
https://www.ncbi.nlm.nih.gov/pubmed/30883989
http://dx.doi.org/10.1111/cpr.12590