Cargando…

5‐ARI induces autophagy of prostate epithelial cells through suppressing IGF‐1 expression in prostate fibroblasts

OBJECTIVES: 5α‐reductase inhibitor (5‐ARI) is a commonly used medicine in the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Our study mainly focuses on the mechanism of BPH development after 5ARI treatment. MATERIALS AND METHODS: Prostate specim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Bo‐Yu, Jiang, Chen‐Yi, Dai, Chen‐Yun, Zhao, Rui‐Zhe, Wang, Xing‐Jie, Zhu, Yi‐Ping, Qian, Yu‐Xin, Yin, Fu‐Li, Fu, Xiang‐Yu, Jing, Yi‐Feng, Han, Bang‐Min, Xia, Shu‐Jie, Ruan, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536403/ https://www.ncbi.nlm.nih.gov/pubmed/30883989 http://dx.doi.org/10.1111/cpr.12590

Ejemplares similares

Deregulation of ATG9A by impaired AR signaling induces autophagy in prostate stromal fibroblasts and promotes BPH progression
por: Jiang, Chen-Yi, et al.
Publicado: (2018)

SIRT7 depletion inhibits cell proliferation and androgen-induced autophagy by suppressing the AR signaling in prostate cancer
por: Ding, Mao, et al.
Publicado: (2020)

LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11
por: Jiang, Chen-Yi, et al.
Publicado: (2016)

Crosstalk between apoptosis and autophagy in prostate epithelial cells under androgen deprivation
por: Liu, Rong-Fu, et al.
Publicado: (2018)

Inhibition of Both EGFR and IGF1R Sensitized Prostate Cancer Cells to Radiation by Synergistic Suppression of DNA Homologous Recombination Repair
por: Wang, Yong, et al.
Publicado: (2013)

Redundant prepuce increases the odds of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)
por: Zhao, Yu-Yang, et al.
Publicado: (2014)

PLZF Mediates the PTEN/AKT/FOXO3a Signaling in Suppression of Prostate Tumorigenesis
por: Cao, JingPing, et al.
Publicado: (2013)

The intriguing role of fibroblasts and c-Jun in the chemopreventive and therapeutic effect of finasteride on xenograft models of prostate cancer
por: Niu, Yi-Nong, et al.
Publicado: (2016)

Roles of autophagy in androgen-induced benign prostatic hyperplasia in castrated rats
por: Liu, Rong-Fu, et al.
Publicado: (2018)

Macrophages are targets of retinoic acid signaling during the wound-healing process after thulium laser resection of the prostate
por: Yu, Dian-Jun, et al.
Publicado: (2017)

Autophagy in Prostate Cancer and Androgen Suppression Therapy
por: Ziparo, Elio, et al.
Publicado: (2013)

Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells
por: Lin, Ji-Fan, et al.
Publicado: (2017)

Re-epithelialization of the prostatic urethra after two-micron laser resection of the prostate
por: Luo, Guang-Heng, et al.
Publicado: (2016)

Connecting the Dots Between the Gut–IGF-1–Prostate Axis: A Role of IGF-1 in Prostate Carcinogenesis
por: Matsushita, Makoto, et al.
Publicado: (2022)

Cancer-associated fibroblasts promote malignant phenotypes of prostate cancer cells via autophagy: Cancer-associated fibroblasts promote prostate cancer development
por: Liu, XuKai, et al.
Publicado: (2023)

Organoid culture systems for prostate epithelial tissue and prostate cancer tissue
por: Drost, Jarno, et al.
Publicado: (2016)

Two-micrometer thulium laser resection of the prostate-tangerine technique in benign prostatic hyperplasia patients with previously negative transrectal prostate biopsy
por: Zhuo, Jian, et al.
Publicado: (2017)

Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
por: He, Shou-Di, et al.
Publicado: (2020)

Low serum testosterone predicts upgrading and upstaging of prostate cancer after radical prostatectomy
por: Gao, Yuan, et al.
Publicado: (2016)

Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression
por: Zeng, Huizhi, et al.
Publicado: (2018)

Comparison of diagnostic efficacy between transrectal and transperineal prostate biopsy: a propensity score-matched study
por: Jiang, Chen-Yi, et al.
Publicado: (2019)

HDAC Inhibition Impedes Epithelial-Mesenchymal Plasticity and Suppresses Metastatic, Castration-Resistant Prostate Cancer
por: Ruscetti, Marcus, et al.
Publicado: (2015)

Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells
por: Xia, Qinghua, et al.
Publicado: (2016)

Applications of circulating tumor cells for prostate cancer
por: Cheng, Shirley, et al.
Publicado: (2016)

An unusual case of retrovesical ectopic prostate tissue accompanied by primary prostate cancer
por: Tan, Fu-Qing, et al.
Publicado: (2012)

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2020)

Peripheral zone PSA density: a predominant variable to improve prostate cancer detection efficiency in men with PSA higher than 4 ng ml(–1)
por: Wang, Cheng, et al.
Publicado: (2021)

Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells
por: Jaeschke, A., et al.
Publicado: (2020)

Clinical efficacy and complications of transurethral resection of the prostate versus plasmakinetic enucleation of the prostate
por: Yang, Chong-Yi, et al.
Publicado: (2023)

Dihydroartemisinin attenuates benign prostatic hyperplasia in rats by inhibiting prostatic epithelial cell proliferation
por: Zhang, Bo, et al.
Publicado: (2021)

Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment
por: Yeh, Chiuan-Ren, et al.
Publicado: (2016)

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R
por: Jia, Cheng You, et al.
Publicado: (2011)

A correlative study of iron metabolism based on q-Dixon MRI in benign prostatic hyperplasia and prostate cancer
por: Tian, Zhen, et al.
Publicado: (2022)

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2023)

Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p
por: Yu, Yu-Zhong, et al.
Publicado: (2022)

Progress in Clinical Research on Gonadotropin-Releasing Hormone Receptor Antagonists for the Treatment of Prostate Cancer
por: Liu, Yi-Fu, et al.
Publicado: (2021)

Resveratrol Suppresses Prostate Cancer Epithelial Cell Scatter/Invasion by Targeting Inhibition of Hepatocyte Growth Factor (HGF) Secretion by Prostate Stromal Cells and Upregulation of E-cadherin by Prostate Cancer Epithelial Cells
por: Hsieh, Tze-chen, et al.
Publicado: (2020)

Genetic Polymorphisms in IGF-I and IGFBP-3 Are Associated with Prostate Cancer in the Chinese Population
por: Qian, Jian, et al.
Publicado: (2014)

Characterization of the complete mitochondrial genome sequence of Jialuo sheep (Ovis aries)
por: Fu, Donghai, et al.
Publicado: (2019)

Discovery of a Novel Bloom’s Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer
por: Ma, Xiao-Yan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t4tbuhg1i1djig2n5nhl5i1p35