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δ‐Tocotrienol induces apoptosis, involving endoplasmic reticulum stress and autophagy, and paraptosis in prostate cancer cells

OBJECTIVES: Prostate cancer, after the phase of androgen dependence, may progress to the castration‐resistant prostate cancer (CRPC) stage, with resistance to standard therapies. Vitamin E‐derived tocotrienols (TTs) possess a significant antitumour activity. Here, we evaluated the anti‐cancer proper...

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Detalles Bibliográficos
Autores principales: Fontana, Fabrizio, Moretti, Roberta Manuela, Raimondi, Michela, Marzagalli, Monica, Beretta, Giangiacomo, Procacci, Patrizia, Sartori, Patrizia, Montagnani Marelli, Marina, Limonta, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536411/
https://www.ncbi.nlm.nih.gov/pubmed/30719778
http://dx.doi.org/10.1111/cpr.12576