Application of ultrasound‐guided cholecystocentesis to the evaluation of the metabolite profiling in bile of dogs and cynomolgus monkeys

In this study, we describe a novel approach for collecting bile from dogs and cynomolgus monkeys for metabolite profiling, ultrasound‐guided cholecystocentesis (UCC). Sampling bile by UCC twice within 24 hours was well tolerated by dogs and monkeys. In studies with atorvastatin (ATV) the metabolite...

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Detalles Bibliográficos
Autores principales: Dierks, Elizabeth A., Luk, Chiuwa E., Cai, Hong, MacGuire, Jamus, Fox, Maxine, Smalley, James, Fancher, R. Marc, Janovitz, Evan, Foster, Kimberly, Sun, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536413/
https://www.ncbi.nlm.nih.gov/pubmed/31149343
http://dx.doi.org/10.1002/prp2.488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536413/
https://www.ncbi.nlm.nih.gov/pubmed/31149343
http://dx.doi.org/10.1002/prp2.488

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