Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study

BACKGROUND: Clinical evidence of lactulose for chronic constipation in Japan was lacking. We performed a randomized, double-blind, placebo-controlled, dose-finding study in Japanese patients with chronic constipation to estimate the optimal clinical dose of lactulose. METHODS: Overall, 250 patients...

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Detalles Bibliográficos
Autores principales: Kasugai, Kunio, Iwai, Hisakazu, Kuboyama, Noboru, Yoshikawa, Aya, Fukudo, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2019
Materias:
Original Article—Alimentary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536483/
https://www.ncbi.nlm.nih.gov/pubmed/30643982
http://dx.doi.org/10.1007/s00535-018-01545-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536483/
https://www.ncbi.nlm.nih.gov/pubmed/30643982
http://dx.doi.org/10.1007/s00535-018-01545-7

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