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Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study

BACKGROUND: Clinical evidence of lactulose for chronic constipation in Japan was lacking. We performed a randomized, double-blind, placebo-controlled, dose-finding study in Japanese patients with chronic constipation to estimate the optimal clinical dose of lactulose. METHODS: Overall, 250 patients...

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Detalles Bibliográficos
Autores principales:	Kasugai, Kunio, Iwai, Hisakazu, Kuboyama, Noboru, Yoshikawa, Aya, Fukudo, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Japan 2019
Materias:	Original Article—Alimentary Tract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536483/ https://www.ncbi.nlm.nih.gov/pubmed/30643982 http://dx.doi.org/10.1007/s00535-018-01545-7

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