Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway

Prior studies have reported the presence of lung fibrosis and enhanced airway hyperresponsiveness (AHR) in mice with high-fat-diet (HFD)-induced obesity. This study evaluated the role of TGF-β1 in HFD-induced AHR and lung fibrosis in a murine model. We generated HFD-induced obesity mice and performe...

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Detalles Bibliográficos
Autores principales: Park, Yoon Hee, Oh, Eun Yi, Han, Heejae, Yang, Misuk, Park, Hye Jung, Park, Kyung Hee, Lee, Jae-Hyun, Park, Jung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536500/
https://www.ncbi.nlm.nih.gov/pubmed/31133649
http://dx.doi.org/10.1038/s12276-019-0258-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536500/
https://www.ncbi.nlm.nih.gov/pubmed/31133649
http://dx.doi.org/10.1038/s12276-019-0258-7

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