Cargando…

Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway

Prior studies have reported the presence of lung fibrosis and enhanced airway hyperresponsiveness (AHR) in mice with high-fat-diet (HFD)-induced obesity. This study evaluated the role of TGF-β1 in HFD-induced AHR and lung fibrosis in a murine model. We generated HFD-induced obesity mice and performe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Yoon Hee, Oh, Eun Yi, Han, Heejae, Yang, Misuk, Park, Hye Jung, Park, Kyung Hee, Lee, Jae-Hyun, Park, Jung-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536500/ https://www.ncbi.nlm.nih.gov/pubmed/31133649 http://dx.doi.org/10.1038/s12276-019-0258-7

Ejemplares similares

Empagliflozin and Dulaglutide are Effective against Obesity-induced Airway Hyperresponsiveness and Fibrosis in A Murine Model
por: Park, Hye Jung, et al.
Publicado: (2019)

High fat diet induces airway hyperresponsiveness in mice
por: Fricke, Kathrin, et al.
Publicado: (2018)

Toxic and adjuvant effects of silica nanoparticles on ovalbumin-induced allergic airway inflammation in mice
por: Han, Heejae, et al.
Publicado: (2016)

Association of Specific Immunoglobulin E to Staphylococcal Enterotoxin with Airway Hyperresponsiveness in Asthma Patients
por: Kim, Seong Han, et al.
Publicado: (2016)

Attenuation of allergic airway inflammation and hyperresponsiveness in a murine model of asthma by silver nanoparticles
por: Park, Hee Sun, et al.
Publicado: (2010)

Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics
por: Park, Hye Jung, et al.
Publicado: (2015)

The Usefulness of FEF(25–75) in Predicting Airway Hyperresponsiveness to Mannitol
por: Kim, Youlim, et al.
Publicado: (2021)

Eosinophilic Airway Inflammation and Airway Hyperresponsiveness According to Aeroallergen Sensitization Pattern in Patients With Lower Airway Symptoms
por: Jo, Eun-Jung, et al.
Publicado: (2014)

Caloric restriction prevents the development of airway hyperresponsiveness in mice on a high fat diet
por: Younas, Haris, et al.
Publicado: (2019)

Atopy May Be an Important Determinant of Subepithelial Fibrosis in Subjects with Asymptomatic Airway Hyperresponsiveness
por: Sohn, Seong-Wook, et al.
Publicado: (2008)

Obesity Increases Airway Hyperresponsiveness via the TNF-α Pathway and Treating Obesity Induces Recovery
por: Kim, Joo Young, et al.
Publicado: (2015)

Volatile Organic Compounds Contribute to Airway Hyperresponsiveness
por: Jang, An-Soo, et al.
Publicado: (2007)

Airway Responsiveness to Inhaled Aspirin is Influenced by Airway Hyperresponsiveness in Asthmatic Patients
por: Kim, Sungsoo, et al.
Publicado: (2010)

Maternal high‐fat diet in mice leads to innate airway hyperresponsiveness in the adult offspring
por: MacDonald, Kelvin D., et al.
Publicado: (2017)

Rhinitis Patients With Sputum Eosinophilia Show Decreased Lung Function in the Absence of Airway Hyperresponsiveness
por: Yang, Min-Suk, et al.
Publicado: (2013)

Complete Resolution of Airway Hyperresponsiveness in Aspirin-sensitive Asthmatic Patients
por: Park, Hae-Sim
Publicado: (1996)

Effects of Diet-Induced Mild Obesity on Airway Hyperreactivity and Lung Inflammation in Mice
por: Jung, Sun Hee, et al.
Publicado: (2013)

Effects of Particulate Matter 10 Inhalation on Lung Tissue RNA expression in a Murine Model
por: Han, Heejae, et al.
Publicado: (2021)

Chronic Low Dose Chlorine Exposure Aggravates Allergic Inflammation and Airway Hyperresponsiveness and Activates Inflammasome Pathway
por: Kim, Sae-Hoon, et al.
Publicado: (2014)

The Effect of Passive Smoking on Asthma Symptoms, Atopy, and Airway Hyperresponsiveness in Schoolchildren
por: Jang, An-Soo, et al.
Publicado: (2004)

Experimental Models of Airway Hyperresponsiveness
por: O'Byrne, Paul M., et al.
Publicado: (2005)

Particulate matter(10)-induced airway inflammation and fibrosis can be regulated by chitinase-1 suppression
por: Choi, Yong Jun, et al.
Publicado: (2023)

Soluble CD93 in Serum as a Marker of Allergic Inflammation
por: Park, Hye Jung, et al.
Publicado: (2017)

Ultra-high-resolution computed tomography shows changes in the lungs related with airway hyperresponsiveness in a murine asthma model
por: Jung, Jae-Woo, et al.
Publicado: (2021)

Severe Airway Hyperresponsiveness in School-aged Boys with a High Body Mass Index
por: Jang, An-Soo, et al.
Publicado: (2006)

The administration of clopidogrel attenuates airway hyperresponsiveness and airway inflammation in an ovalbumin specific allergic asthma model
por: Trinh, Hoang Kim Tu, et al.
Publicado: (2015)

Role of Abl in airway hyperresponsiveness and airway remodeling
por: Cleary, Rachel A, et al.
Publicado: (2013)

Effects of lobeglitazone on insulin resistance and hepatic steatosis in high-fat diet-fed mice
por: Choi, Bong-Hoi, et al.
Publicado: (2018)

Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet
por: Lee, Hee Sun, et al.
Publicado: (2008)

Allomyrina dichotoma Larva Extract Ameliorates the Hepatic Insulin Resistance of High-Fat Diet-Induced Diabetic Mice
por: Kim, Kyong, et al.
Publicado: (2019)

A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness
por: Gordon, E D, et al.
Publicado: (2012)

Sicyos angulatus Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
por: Choi, Ji Hyun, et al.
Publicado: (2020)

Airway Inflammation and Allergen Specific IgE Production May Persist Longer Than Airway Hyperresponsiveness in Mice
por: Chang, Yoon-Seok, et al.
Publicado: (2004)

Metformin Alleviates Airway Hyperresponsiveness in a Mouse Model of Diet-Induced Obesity
por: Gu, Chenjuan, et al.
Publicado: (2022)

Modulation of airway hyperresponsiveness by rhinovirus exposure
por: Lo, Dennis, et al.
Publicado: (2018)

Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition
por: Cho, Jang-Hee, et al.
Publicado: (2016)

Administration of Tonsil-Derived Mesenchymal Stem Cells Improves Glucose Tolerance in High Fat Diet-Induced Diabetic Mice via Insulin-Like Growth Factor-Binding Protein 5-Mediated Endoplasmic Reticulum Stress Modulation
por: Lee, Younghay, et al.
Publicado: (2019)

Additive Effect of Diesel Exhaust Particulates and Ozone on Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma
por: Jang, An-Soo, et al.
Publicado: (2005)

Time Sequence of Airway Remodeling in a Mouse Model of Chronic Asthma: the Relation with Airway Hyperresponsiveness
por: Kim, Seung Joon, et al.
Publicado: (2007)

Fasting serum insulin levels and insulin resistance are associated with colorectal adenoma in Koreans
por: Kim, Eun Hee, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_r28o0es9gph73tduv7ff258pjt