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Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536510/ https://www.ncbi.nlm.nih.gov/pubmed/31133647 http://dx.doi.org/10.1038/s41598-019-44358-1 |