A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52

Tripartite motif protein 52 (TRIM52) is a non-canonical TRIM family member harbouring the largest RING domain encoded in the human genome. In humans TRIM52 is conserved and has been under positive selection pressure, yet it has been lost in many non-primates. Competitive cell fitness assays demonstr...

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Detalles Bibliográficos
Autores principales: Hacker, Kathrin, Benke, Stefan, Agerer, Benedikt, Scinicariello, Sara, Budroni, Valentina, Versteeg, Gijs A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536530/
https://www.ncbi.nlm.nih.gov/pubmed/31133683
http://dx.doi.org/10.1038/s41598-019-44359-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536530/
https://www.ncbi.nlm.nih.gov/pubmed/31133683
http://dx.doi.org/10.1038/s41598-019-44359-0

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