Cargando…
A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52
Tripartite motif protein 52 (TRIM52) is a non-canonical TRIM family member harbouring the largest RING domain encoded in the human genome. In humans TRIM52 is conserved and has been under positive selection pressure, yet it has been lost in many non-primates. Competitive cell fitness assays demonstr...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536530/ https://www.ncbi.nlm.nih.gov/pubmed/31133683 http://dx.doi.org/10.1038/s41598-019-44359-0 |