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Association between APOE4 and biomarkers in cerebral adrenoleukodystrophy

Cerebral adrenoleukodystrophy (cALD) is an inflammatory neurodegenerative disease associated with mutation of the ABCD1 gene. Proteomic analysis of cerebral spinal fluid (CSF) from young males with active cALD revealed markers of inflammation including APOE4. APOE4 genotype has been associated with...

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Detalles Bibliográficos
Autores principales: Orchard, Paul J., Markowski, Todd W., Higgins, LeeAnn, Raymond, Gerald V., Nascene, David R., Miller, Weston P., Pierpont, Elizabeth I., Lund, Troy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536544/
https://www.ncbi.nlm.nih.gov/pubmed/31133696
http://dx.doi.org/10.1038/s41598-019-44140-3