Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

Variability in bacterial sterilization is a key feature of Mycobacterium tuberculosis (Mtb) disease. In a population of human macrophages, there are macrophages that restrict Mtb growth and those that do not. However, the sources of heterogeneity in macrophage state during Mtb infection are poorly u...

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Detalles Bibliográficos
Autores principales: Bryson, Bryan D., Rosebrock, Tracy R., Tafesse, Fikadu G., Itoh, Christopher Y., Nibasumba, Armel, Babunovic, Gregory H., Corleis, Bjorn, Martin, Constance, Keegan, Caroline, Andrade, Priscila, Realegeno, Susan, Kwon, Douglas, Modlin, Robert L., Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536549/
https://www.ncbi.nlm.nih.gov/pubmed/31133636
http://dx.doi.org/10.1038/s41467-019-10065-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536549/
https://www.ncbi.nlm.nih.gov/pubmed/31133636
http://dx.doi.org/10.1038/s41467-019-10065-8

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