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Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
Variability in bacterial sterilization is a key feature of Mycobacterium tuberculosis (Mtb) disease. In a population of human macrophages, there are macrophages that restrict Mtb growth and those that do not. However, the sources of heterogeneity in macrophage state during Mtb infection are poorly u...
Autores principales: | Bryson, Bryan D., Rosebrock, Tracy R., Tafesse, Fikadu G., Itoh, Christopher Y., Nibasumba, Armel, Babunovic, Gregory H., Corleis, Bjorn, Martin, Constance, Keegan, Caroline, Andrade, Priscila, Realegeno, Susan, Kwon, Douglas, Modlin, Robert L., Fortune, Sarah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536549/ https://www.ncbi.nlm.nih.gov/pubmed/31133636 http://dx.doi.org/10.1038/s41467-019-10065-8 |
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