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AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction

The AXL receptor tyrosine kinase (RTK) is involved in partial epithelial‐to‐mesenchymal transition (EMT) and inflammation – both main promoters of renal fibrosis development. The study aim was to investigate the role of AXL inhibition in kidney fibrosis due to unilateral ureteral obstruction (UUO)....

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Detalles Bibliográficos
Autores principales: Landolt, Lea, Furriol, Jessica, Babickova, Janka, Ahmed, Lavina, Eikrem, Øystein, Skogstrand, Trude, Scherer, Andreas, Suliman, Salwa, Leh, Sabine, Lorens, James B., Gausdal, Gro, Marti, Hans‐Peter, Osman, Tarig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536582/
https://www.ncbi.nlm.nih.gov/pubmed/31134766
http://dx.doi.org/10.14814/phy2.14091