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AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction
The AXL receptor tyrosine kinase (RTK) is involved in partial epithelial‐to‐mesenchymal transition (EMT) and inflammation – both main promoters of renal fibrosis development. The study aim was to investigate the role of AXL inhibition in kidney fibrosis due to unilateral ureteral obstruction (UUO)....
Autores principales: | Landolt, Lea, Furriol, Jessica, Babickova, Janka, Ahmed, Lavina, Eikrem, Øystein, Skogstrand, Trude, Scherer, Andreas, Suliman, Salwa, Leh, Sabine, Lorens, James B., Gausdal, Gro, Marti, Hans‐Peter, Osman, Tarig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536582/ https://www.ncbi.nlm.nih.gov/pubmed/31134766 http://dx.doi.org/10.14814/phy2.14091 |
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