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Learning Causal Biological Networks With the Principle of Mendelian Randomization

Although large amounts of genomic data are available, it remains a challenge to reliably infer causal (i. e., regulatory) relationships among molecular phenotypes (such as gene expression), especially when multiple phenotypes are involved. We extend the interpretation of the Principle of Mendelian r...

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Detalles Bibliográficos
Autores principales: Badsha, Md. Bahadur, Fu, Audrey Qiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536645/
https://www.ncbi.nlm.nih.gov/pubmed/31164902
http://dx.doi.org/10.3389/fgene.2019.00460