Could an Impairment in Local Translation of mRNAs in Glia be Contributing to Pathogenesis in ALS?

One of the key pathways implicated in amyotrophic lateral sclerosis (ALS) pathogenesis is abnormal RNA processing. Studies to date have focussed on defects in RNA stability, splicing, and translation, but this review article will focus on the largely overlooked RNA processing mechanism of RNA traffi...

Descripción completa

Detalles Bibliográficos
Autores principales: Barton, Samantha K., Gregory, Jenna M., Chandran, Siddharthan, Turner, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536688/
https://www.ncbi.nlm.nih.gov/pubmed/31164803
http://dx.doi.org/10.3389/fnmol.2019.00124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536688/
https://www.ncbi.nlm.nih.gov/pubmed/31164803
http://dx.doi.org/10.3389/fnmol.2019.00124

Ejemplares similares