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Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells
Introduction: Increased iron content in cancer cells is associated with resistance to chemotherapy. Recent studies have demonstrated that estrogen (E(2)) suppresses hepcidin synthesis and enhances intracellular iron efflux. Herein, we investigated whether E(2)-driven intracellular iron efflux render...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536718/ https://www.ncbi.nlm.nih.gov/pubmed/31213891 http://dx.doi.org/10.2147/CMAR.S204852 |