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The hypoxia-response pathway modulates RAS/MAPK–mediated cell fate decisions in Caenorhabditis elegans

Animals need to adjust many cellular functions to oxygen availability to adapt to changing environmental conditions. We have used the nematode Caenorhabditis elegans as a model to investigate how variations in oxygen concentrations affect cell fate specification during development. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Maxeiner, Sabrina, Grolleman, Judith, Schmid, Tobias, Kammenga, Jan, Hajnal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536719/
https://www.ncbi.nlm.nih.gov/pubmed/31126994
http://dx.doi.org/10.26508/lsa.201800255