Blood leukocyte LINE-1 hypomethylation and oxidative stress in knee osteoarthritis

AIM: Joints inflammation is one of the most pathologic processes leading to the development of osteoarthritis (OA), possibly leading to genomic instability. LINE-1 is transposable elements, and alterations in LINE-1 methylation induced by 8-hydroxy-2′-deoxyguanosine (8-OHdG) can cause genomic instab...

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Detalles Bibliográficos
Autores principales: Teerawattanapong, Nipaporn, Udomsinprasert, Wanvisa, Ngarmukos, Srihatach, Tanavalee, Aree, Honsawek, Sittisak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536726/
https://www.ncbi.nlm.nih.gov/pubmed/31193532
http://dx.doi.org/10.1016/j.heliyon.2019.e01774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536726/
https://www.ncbi.nlm.nih.gov/pubmed/31193532
http://dx.doi.org/10.1016/j.heliyon.2019.e01774

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