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Blood leukocyte LINE-1 hypomethylation and oxidative stress in knee osteoarthritis
AIM: Joints inflammation is one of the most pathologic processes leading to the development of osteoarthritis (OA), possibly leading to genomic instability. LINE-1 is transposable elements, and alterations in LINE-1 methylation induced by 8-hydroxy-2′-deoxyguanosine (8-OHdG) can cause genomic instab...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536726/ https://www.ncbi.nlm.nih.gov/pubmed/31193532 http://dx.doi.org/10.1016/j.heliyon.2019.e01774 |