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Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

In addition to its implication in hereditary hearing loss, the Gasdermin E (GSDME) gene is also a tumor suppressor involved in cancer progression through programmed cell death. GSDME epigenetic silencing through methylation has been shown in some cancer types, but studies are yet to fully explore it...

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Detalles Bibliográficos
Autores principales: Ibrahim, Joe, Op de Beeck, Ken, Fransen, Erik, Croes, Lieselot, Beyens, Matthias, Suls, Arvid, Vanden Berghe, Wim, Peeters, Marc, Van Camp, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536921/
https://www.ncbi.nlm.nih.gov/pubmed/30993897
http://dx.doi.org/10.1002/cam4.2103