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Hyperammonemia after capecitabine associated with occult impairment of the urea cycle

BACKGROUND: Cancer patients receiving chemotherapy often complain of “chemobrain” or cognitive impairment, but mechanisms remain elusive. METHODS: A patient with gastric cancer developed delirium and hyperammonemia after chemotherapy with the 5‐fluorouracil pro‐drug capecitabine. Exome sequencing fa...

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Detalles Bibliográficos
Autores principales: Chu, Gilbert, Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536928/
https://www.ncbi.nlm.nih.gov/pubmed/30977266
http://dx.doi.org/10.1002/cam4.2036