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LukS‐PV induces apoptosis in acute myeloid leukemia cells mediated by C5a receptor

LukS‐PV is one of the two components of Panton‐Valentine leucocidin (PVL). Our previous study showed that LukS‐PV can induce apoptosis in human acute myeloid leukemia (AML) THP‐1 and HL‐60 cells. C5aR (C5a receptor) is the receptor for PVL, but whether C5aR plays a key role in LukS‐PV induced apopto...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Yu, Wen‐Wei, Peng, Jing, Xu, Liang‐Fei, Zhao, Chang‐Cheng, Chang, Wen‐Jiao, Ma, Xiao‐Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536962/
https://www.ncbi.nlm.nih.gov/pubmed/30955242
http://dx.doi.org/10.1002/cam4.2137