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Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation

Intrauterine hypoxia (IUH) is a common intrauterine dysplasia that can cause programming of the offspring cardiovascular system. In this study, we hypothesized that placental treatment with spermidine (SPD) can prevent heart injury in neonatal offspring exposed to IUH. Pregnant rats were exposed to...

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Detalles Bibliográficos
Autores principales: Chai, Nannan, Zhang, Hao, Li, Lingxu, Yu, Xue, Liu, Yan, Lin, Yan, Wang, Lina, Yan, Jiamin, Nikolaevna, Sazonova Elena, Zhao, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537013/
https://www.ncbi.nlm.nih.gov/pubmed/31217839
http://dx.doi.org/10.1155/2019/5406468