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Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation
Intrauterine hypoxia (IUH) is a common intrauterine dysplasia that can cause programming of the offspring cardiovascular system. In this study, we hypothesized that placental treatment with spermidine (SPD) can prevent heart injury in neonatal offspring exposed to IUH. Pregnant rats were exposed to...
Autores principales: | Chai, Nannan, Zhang, Hao, Li, Lingxu, Yu, Xue, Liu, Yan, Lin, Yan, Wang, Lina, Yan, Jiamin, Nikolaevna, Sazonova Elena, Zhao, Yajun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537013/ https://www.ncbi.nlm.nih.gov/pubmed/31217839 http://dx.doi.org/10.1155/2019/5406468 |
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