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Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers

TNBC is a highly heterogeneous and aggressive breast cancer subtype associated with high relapse rates, and for which no targeted therapy yet exists. Protein arginine methyltransferase 5 (PRMT5), an enzyme which catalyzes the methylation of arginines on histone and non‐histone proteins, has recently...

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Detalles Bibliográficos
Autores principales: Vinet, Mathilde, Suresh, Samyuktha, Maire, Virginie, Monchecourt, Clarisse, Némati, Fariba, Lesage, Laetitia, Pierre, Fabienne, Ye, Mengliang, Lescure, Auriane, Brisson, Amélie, Meseure, Didier, Nicolas, André, Rigaill, Guillem, Marangoni, Elisabetta, Del Nery, Elaine, Roman‐Roman, Sergio, Dubois, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537044/
https://www.ncbi.nlm.nih.gov/pubmed/30957988
http://dx.doi.org/10.1002/cam4.2114