Constrained instruments and their application to Mendelian randomization with pleiotropy

In Mendelian randomization (MR), inference about causal relationship between a phenotype of interest and a response or disease outcome can be obtained by constructing instrumental variables from genetic variants. However, MR inference requires three assumptions, one of which is that the genetic vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Lai, Oualkacha, Karim, Didelez, Vanessa, Ciampi, Antonio, Rosa‐Neto, Pedro, Benedet, Andrea L., Mathotaarachchi, Sulantha, Richards, John Brent, Greenwood, Celia M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537099/
https://www.ncbi.nlm.nih.gov/pubmed/30635941
http://dx.doi.org/10.1002/gepi.22184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537099/
https://www.ncbi.nlm.nih.gov/pubmed/30635941
http://dx.doi.org/10.1002/gepi.22184

Ejemplares similares