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Dynamic lipid mediator changes support macrophage subtype transitions during muscle regeneration

Muscle damage elicits a sterile immune response that facilitates complete regeneration. Here, we utilized mass spectrometry-based lipidomics to map the mediator lipidome during the transition from inflammation to resolution and regeneration in skeletal muscle injury. We observed the temporal regulat...

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Detalles Bibliográficos
Autores principales: Giannakis, Nikolas, Sansbury, Brian E., Patsalos, Andreas, Hays, Tristan T., Riley, Colin O., Han, Xianlin, Spite, Matthew, Nagy, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537107/
https://www.ncbi.nlm.nih.gov/pubmed/30936495
http://dx.doi.org/10.1038/s41590-019-0356-7