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Do the charges matter?—balancing the charges of the chromodomain proteins on the nucleosome

The chromodomain (CD) is a member of the Royal family of conserved chromatin-binding motifs with methylated substrate binding ability, and is often found in ‘readers’ or ‘writers’ of repressive histone marks. The regions upstream or downstream of the CD are generally highly charged. Several previous...

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Detalles Bibliográficos
Autores principales: Hiragami-Hamada, Kyoko, Nakayama, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537122/
https://www.ncbi.nlm.nih.gov/pubmed/30649341
http://dx.doi.org/10.1093/jb/mvz004