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Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture
OBJECTIVE: Recombinant immunotoxins (RITs) are antibody-toxin fusion proteins that can selectively eliminate populations of cells expressing specific surface receptors. They are in evaluation as therapeutic agents for cancer. RITs based on Pseudomonas exotoxin A (PE) are in use clinically for the tr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537151/ https://www.ncbi.nlm.nih.gov/pubmed/31133049 http://dx.doi.org/10.1186/s13104-019-4337-6 |